Abstract: Rolling process parameters of DH36 high strength ship plate steel in Baosteel were simulated and optimized with a selfdeveloped and designed large-specimen plane strain thermo-mechanical simulator. The flow stress was measured in the process of deformation. Microstructure observations, round stick tension and Charpy V-notch impact tests of simulated specimens were carried out. The results show that large-specimen plane strain simulation technology not only meets the requirement of microstructure analysis like a general thermo-simulation system, but also the mechanical properties of the specimens can be analyzed after simulation. Experimental data show that the simulated ship plate steel provides with excellent mechanical properties.