Abstract: A study was carried out to find out the suitable conditions for zinc extraction from acidic zinc sulfate solution by two different extractant systems of di-(2-ethylhexy)-dithiophosphoric acid (D2EHPA) and D2EHPA-Trioctylamine(TOA) respectively in the background of comprehensive utilization of sulfureted sodium. The result shows that the D2EHPA-TOA synergistic extractant system is prior to the D2EHPA one without TOA when the degrees of extraction and strip and the economic benefits are taken into account. A technique to reclaim zinc from bacterial leach solution is suggested.